Li-resin structure

Li-Resin was coined owing to the innovation by Dr. Yongfu Li, the chief scientist of Biotide Core, LLC, who improved the polymerization technology which is a proprietary, cross-linked polyacrylic amide solid support suitable for synthesis of peptide and other bio-molecules. The structure of the resin was made only of amide bonds to procure the chemical stability required to avoid decomposition or degradation. The solid-phase support contains a uniform distribution of amine as active group for solid-phase synthesis.

The resin structure was selected to obtain a loading of ca 0.5 mmol/g. We can also adjust the extent of loading to decrease the reactive sites for synthesis of peptide of high molecular weight or complex structural bio-molecule, or to increase the reactive sites for synthesis of peptide of small molecular weight or simple structural bio-molecule.